Standard Intravitreal Injection Doses
Use this quick reference table when you are ordering injections. All of these dosages are verified from primary literature (see end of article for links) and represent the most common concentrations of various ophthalmic intravitreal drugs.
Injection | Standard Dose | Common Indications |
Bevacizumab (Avastin) | 1.25 mg/0.05 mL | Wet AMD, CME, Vein Occlusion |
Ranibizumab (Lucentis) | 0.5 mg/0.05 mL | Wet AMD, CME, Vein Occlusion |
Aflibercept (Eylea) | 2 mg/0.05 mL | Wet AMD, CME, Vein Occlusion |
Triamcinolone acetonide (Kenalog/Triescence) | 4 mg/0.10 mL | CME resistant to anti-VEGF |
Vancomycin | 1 mg/0.10 mL | Endophthalmitis |
Ceftazidime | 2.25/0.10 mL | Endophthalmitis |
Dexamethasone | 0.4 mg/0.10 mL | Endophthalmitis adjunctive |
Dexmethasone Implant (Ozurdex) | 0.7mg | CME resistant to anti-VEGF |
Ganciclovir | 2 mg/0.05 mL | Viral Infection (ie CMV, HSV, VZV) |
Foscarnet | 2.4 mg/0.10 mL | Viral Infection (ie CMV, HSV, VZV) |
Amphotericin | 5 ug/0.05 mL | Antifungal |
Voriconazole | 50-100 ug/0.10 mL | Antifungal |
Clindamycin | 1 mg/0.10 mL | Toxoplasmosis |
Instructional Video
References / Further Reading
Avastin: http://www.ncbi.nlm.nih.gov/pubmed/19584648
Lucentis: http://www.gene.com/download/pdf/lucentis_prescribing.pdf
Eylea: https://www.regeneron.com/Eylea/eylea-fpi.pdf
Triescence: https://www.myalcon.com/docs/ars-TRIESENCE-fact-sheet-single.pdf
Vancomycin: http://www.ncbi.nlm.nih.gov/pubmed/1101624
Ceftazidime: http://www.ncbi.nlm.nih.gov/pubmed/19584648
Dexamethasone: http://www.ncbi.nlm.nih.gov/pubmed/21289020
Ganciclovir: http://www.ncbi.nlm.nih.gov/pubmed/8703858
Foscarnet: http://www.ncbi.nlm.nih.gov/pubmed/19584648
Amphotericin: http://www.ncbi.nlm.nih.gov/pubmed/19584648
Voriconazole: http://www.ncbi.nlm.nih.gov/pubmed/19584648
Clindamycin: http://www.ncbi.nlm.nih.gov/pubmed/20708269
Just a suggestion to add up the clinical trials involving intravitreal injections in this blog